GEM – Genetic, environmental, microbial project
Study code
NBR12
Lead researcher
Dr Miles Parkes
Study type
Participant re-contact
Institution or company
University of Cambridge
Researcher type
Non-commercial
Speciality area
Genomics and Rare Diseases, Gastroenterology
Summary
The goal of the GEM study is to identify environmental and microbial risk factors for Crohn’s disease by prospectively recruiting and sampling from a large cohort of individuals who are at high risk of developing Crohn’s disease by virtue of having an affected first degree relative. This reduces the confounding effect that gut inflammation has on the gut microbiota – which has always fundamentally undermined attempts to define microbial triggers for IBD.