CMV infection in inflammatory bowel disease
Study code
NBR22
Lead researcher
Prof. Holm Uhlig
Study type
Samples and data
Institution or company
University of Oxford
Researcher type
Non-commercial
Speciality area
Gastroenterology, Infection
Summary
Cytomegalovirus (CMV) infection has a massive – but subclinical - impact on host immunity, Despite its long association with the gut, however, little is known about its impact in the steady state and interaction with genetic risk factors.
We aim to replicate and confirm findings that CMV infection is associated with the development of ulcerated colitis (UC) and to define the relationship to known UC genetic risk factors.